| Syllabus | Assignments |

BIOL.670.01, BIOL.470.01 - Statistical Analysis for Bioinformatics
Online Course, Spring 2017
Herbert J. Bernstein ()
Quiz 6

 

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This web page is www.bernstein-plus-sons.com/.rit/BIOL670S17/BIOL670_Quiz_6.html

This is the 6th quiz for BIOL 670/470 to be taken on Thursday, 23 March 2017 or Tuesday 28 March 2017 during the weekly e-meeting. You have 10 minutes to answer the two questions. You may use the notes on your blog, but the answers are not just waiting for you in the book. Thinking is required.

  <==== Do this AFTER you've answered all the questions

You probably DON'T want to do this ===>  

Please fill in the following information:

Name:


Email:

Skype ID:

Blog URL:

Please answer the following questions on this form (or on a paper copy of this form).

  1. Give some serious thought to this question. How can you tell the difference between an anomalous data point that is a statistical outlier that should be discarded and an anomalous data point that is telling you about a significant new result that reflects science that does not fit the model you assumed for the data?

  2. In discussing equivalence testing, the text book returns to blood pressure and asserts that precious few clinicians would change their practice for just 3 mm Hg of difference in the systolic blood pressures of 163 versus 160 of two groups of 400 patients with a standard deviation of 15 mm Hg even though the 3mm Hg difference is statistically significant. Explain why that difference is statistically significant, and explain how you would determine how large a statistically signficiant difference would be clinically significant for blood pressure. Note that you need to specifically consider how you would make a determination of clinical significance.

  <==== Do this AFTER you've answered all the questions

You probably DON'T want to do this ===>  

Revised 19 March 2017